Basic Information
VIS ID
TVIS44026712
Fusion event
HTLV-1-ACACB integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
GRCh37/hg19
Start
109575728/109137923 (Hg38)
End
109575728/109137923 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
ACACB
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-544a ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-4252 ; hsa-mir-6797-3p ; hsa-mir-6076 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-425-5p ; hsa-mir-596 ; hsa-mir-508-5p
Nearest miRNA
hsa-let-7i/Upstream/300917; hsa-mir-1178/Downstream/695425;
Nearest TSS
ENST00000382841/Upstream/6565; ENST00000546328/Downstream/1474;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/26554, chr12-CpG: 34/Downstream/16587
Nearby gene
ACACB(+1474) ;
Upstream sequence
ttgtccaggctggagtgcagtggtgccatcttagctcatttcaacctctgcctcctgggctTTTCttttctttttctttttttttttgtttttgagacca
Downstream sequence
agtctcactctgttgcccgggctggaatgcagttgcatgatctcagctcactgcaacctccacctccaggttcaagtgattctcatgcctcagactcccg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate