Basic Information
VIS ID
TVIS44026713
Fusion event
HTLV-1-MYO1H integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
GRCh37/hg19
Start
109869765/109431960 (Hg38)
End
109869765/109431960 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
MYO1H
miRNAs that regulate target gene
hsa-mir-609 ; hsa-mir-6804-5p ; hsa-mir-219b-3p ; hsa-mir-5699-3p ; hsa-mir-6748-3p ; hsa-mir-4421 ; hsa-mir-450a-2-3p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-500a-3p ; hsa-mir-4652-5p ; hsa-mir-3191-3p ; hsa-mir-3144-5p ; hsa-mir-6804-3p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-6730-3p ; hsa-mir-3189-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-1228-3p ; hsa-mir-6813-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485
Nearest miRNA
hsa-let-7i/Upstream/594954; hsa-mir-1178/Downstream/401388;
Nearest TSS
ENST00000382841/Upstream/30555; ENST00000457826/Downstream/7577;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/121387, chr12-CpG: 44/Downstream/45366
Upstream sequence
caggatctctgttacccaggctggagtgctccctgaagcctcaacctcctggactcaagcgatcctcctgcctcagcctcctgagtagctgggactacag
Downstream sequence
ccgcacactgccacacctggctaaaaaaaaaatttttttttttttttttttttttttttgagatggagtcttgctctgtcgcccaggctggagtacagtg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate