Basic Information
VIS ID
TVIS44026733
Fusion event
HTLV-1-DHX37 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
125459956/124975410 (Hg38)
End
125459956/124975410 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
DHX37
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-193b-3p ; hsa-mir-15b-5p
Nearest miRNA
hsa-let-7i/Upstream/59751; hsa-mir-3612/Downstream/3318682;
Nearest TSS
ENST00000382841/Upstream/8405; ENST00000341446/Downstream/5288;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/46791, chr12-CpG: 35/Downstream/13458
Upstream sequence
ACCCAGCACCCTCGGCACAGATGCTGCTCACCTCCTCCTGGGCTTCCCACATCTGGGCAAGGCCACAGGACCACCCCATAGTCCGCCCCAGGGAAGTAGA
Downstream sequence
GCCCTCACCGCTGGGACAGATTCATCTCCTTGGCCACTCGCTGGGACATGGCCACGGCGGCCACTCGGCGGGGCTCCGTGACACCGATGATGCTGTCTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate