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TVIS44026737
Basic Information
VIS ID
TVIS44026737
Fusion event
HTLV-1-TMEM132B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
126025950/125541404 (Hg38)
End
126025950/125541404 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
TMEM132B
miRNAs that regulate target gene
hsa-mir-221-3p
;
hsa-mir-181a-5p
;
hsa-mir-297
;
hsa-mir-3924
;
hsa-mir-567
;
hsa-mir-602
;
hsa-mir-8485
;
hsa-mir-377-3p
;
hsa-mir-744-3p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-378a-5p
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-6131
;
hsa-mir-6505-3p
;
hsa-mir-617
;
hsa-mir-3663-5p
;
hsa-mir-3653-5p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-3934-5p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-505-3p
;
hsa-mir-4735-5p
;
hsa-mir-4762-5p
;
hsa-mir-1208
;
hsa-mir-1273f
;
hsa-mir-1291
;
hsa-mir-1304-3p
;
hsa-mir-328-3p
;
hsa-mir-4290
;
hsa-mir-4469
;
hsa-mir-6760-3p
;
hsa-mir-6775-3p
;
hsa-mir-6851-3p
Nearest miRNA
hsa-let-7i/Upstream/625745; hsa-mir-3612/Downstream/2752688;
Nearest TSS
ENST00000382841/Upstream/191952;
ENST00000535886/Downstream/81048;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/7585
,
chr12-CpG: 24/Downstream/142490
Upstream sequence
CCAGGCAGCCTCTTATGCGGGAGCTAGGGCTTGACCCTGGCACCCCTGATTCTGTCTGTCCTGACACTGTCTCTTCTGATACAGCCTCTTGGGGTTTTGC
Downstream sequence
ATCACTGGACAGATGTTCACTAAAACAGCCTTCTCTCTCATGTATTTCTTGGCACACAGGATGTGACTGCATGGGCCTTGAAAAGTGAGAGGTTGGAGTg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HTLV-1 carrier#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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