Basic Information
VIS ID
TVIS44026754
Fusion event
HTLV-1-CACNA2D4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
1953752/1844586 (Hg38)
End
1953752/1844586 (Hg38)
Orient
-
Location type
Intronic
Target gene
CACNA2D4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-203b-3p ; hsa-mir-7158-3p
Nearest miRNA
hsa-mir-3649/Upstream/184206; hsa-let-7i/Downstream/5119113;
Nearest TSS
ENST00000382841/Upstream/17023; ENST00000544163/Downstream/9451;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/46987, chr12-CpG: 66/Downstream/19987
Upstream sequence
CAGGGTGAACACGCTGGCCTCGTCCTCAGGTGTCAGGAACTTCCTGCAAGGAGGAAGATGTGGTACCTCTCCCCAGATCTGTGAACACAGTCATCACTCT
Downstream sequence
TTCCTTTTCTCACACAAGGTCAACTTGGCTGGGCTAAGAGAGTGATTTTAGCCCCTAAATTAGTACGGCCCCAGACAATGCTTCCCAGCAATTCTCGCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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