Basic Information
VIS ID
TVIS44026770
Fusion event
HTLV-1-TSPAN11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
31087108/30934174 (Hg38)
End
31087108/30934174 (Hg38)
Orient
+
Location type
Intronic
Target gene
TSPAN11
miRNAs that regulate target gene
hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6799-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6876-5p ; hsa-mir-4476
Nearest miRNA
hsa-mir-1244-3/Upstream/5060095; hsa-let-7i/Downstream/11389526;
Nearest TSS
ENST00000382841/Upstream/7216; ENST00000535317/Downstream/126576;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/7230, chr12-CpG: 67/Downstream/139235
Upstream sequence
ACTGTGGATGCTGGCTTTCAGAGTCATGATTACCCAACTCTCTAGCCTTCTCAAATTTCTGCAAGGCACTAACCCCCAGCTGTTGGGTGGGCCAGGCCCA
Downstream sequence
GGTGGACAGGGGTGACCGGGAAGACCCACTTCAGATGTTTCTGTCTTGGCCCCATGCCTGAGGGGCAGAGCACAGCCAACCAGAGAGGACTCCTGCTCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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