Basic Information
VIS ID
TVIS44026777
Fusion event
HTLV-1-PRMT8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.32
Reference genome
GRCh37/hg19
Start
3662604/3553438 (Hg38)
End
3662604/3553438 (Hg38)
Orient
+
Location type
Intronic
Target gene
PRMT8
miRNAs that regulate target gene
hsa-mir-330-3p ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-2276-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3939 ; hsa-mir-3925-5p
Nearest miRNA
hsa-mir-3649/Upstream/1893058; hsa-let-7i/Downstream/3410261;
Nearest TSS
ENST00000382841/Upstream/15224; ENST00000637958/Downstream/100785;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/59596, chr12-CpG: 59/Downstream/199464
Upstream sequence
GCCATTCTCTGCTGGCCAGGAGCATGAGGTCTGCCAGCCCCTTTTGAGTCTCCAGCACAGAGATCAATCCCTCCATCACGGGTGGTGACTAGACATCAGT
Downstream sequence
CTTTTCGCAAaggcagcccaatttcgtggaaggccgctggccttgaggtgggggggctgggtttcggttttcagtctgccacaaagttgtgatgcagccg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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