Basic Information
VIS ID
TVIS44026778
Fusion event
HTLV-1-CPNE8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
39222710/38828908 (Hg38)
End
39222710/38828908 (Hg38)
Orient
-
Location type
Intronic
Target gene
CPNE8
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-8485 ; hsa-mir-4719
Nearest miRNA
hsa-mir-1244-3/Upstream/12954829; hsa-let-7i/Downstream/3494792;
Nearest TSS
ENST00000382841/Upstream/61191; ENST00000551152/Downstream/76723;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/512067, chr12-CpG: 29/Downstream/76538
Upstream sequence
TGCTCCCTGCCTTATTTGGAACTGGAGGAAACAGAATCAACTCATGCAATTGACATGAAAACTAAACATGATCCTAGTAATTGAAGGTGAAGATGGAATA
Downstream sequence
GACCATTCTTAGTGATTACCTTCTCCCAATATTTACCTACTTACAGCTTTCTCTACAAGCCACTTCCATGGTAAAAATTATTATGAAAATTTCAATAACC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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