Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene481397634784153747943048479729654800455447963569479688784796295847966297479486784795179047945692479478634794294147944374479407384794181647988231479892364796756647968567479539414795466447959834479605004794513847945287479548184795496747960598479607474798155847981707479903984799054747990650
Basic Information
VIS ID
TVIS44026786
Fusion event
HTLV-1-COL2A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
48384433/47990650 (Hg38)
End
48384433/47990650 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
COL2A1
miRNAs that regulate target gene
hsa-mir-106a-5p ; hsa-mir-29b-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/626381; hsa-let-7i/Downstream/142147;
Nearest TSS
ENST00000382841/Upstream/2179; ENST00000546738/Downstream/8209;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/26926, chr12-CpG: 44/Downstream/10935
Upstream sequence
CAGGTTGCCTCTTCCTCTGGCCCATCCCCAGACAGCCTGCTCTTACGGAAAACAAAGATGCCCATAGGATGTCTACCATTGGCTCCCTGATGGGGCAGGG
Downstream sequence
CACCAGCCACAGCTCAAACACTACATCTGAGCTCAAGCCCTAAGAGGCTTTTGCTTACAAAGCAAGGCAAGGTTGCCAGCTCCTTCTCTAGGACTGGACT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate