Basic Information
VIS ID
TVIS44026805
Fusion event
HTLV-1-MFSD5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
53647478/53253694 (Hg38)
End
53647478/53253694 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA12A
Target gene
MFSD5
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-98-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/196682; hsa-let-7i/Downstream/738044;
Nearest TSS
ENST00000382841/Upstream/1245; ENST00000553219/Downstream/14605;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1552, chr12-CpG: 56/Downstream/14450
Upstream sequence
ACCATACAAGCTCTATTTGAGAGTGTCATCTTCATCTTTGTCTTCCTCTGGACACCTGTGCTGGACCCACACGGGGCCCCTCTGGGCATTATCTTCTCCA
Downstream sequence
GCTTCATGGCAGCCAGCCTGCTTGGCTCTTCCCTGTACCGTATCGCCACCTCCAAGAGGTACCACCTTCAGCCCATGCACCTGCTGTCCCTTGCTGTGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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