Basic Information
VIS ID
TVIS44026806
Fusion event
HTLV-1-NFE2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
54693780/54299996 (Hg38)
End
54693780/54299996 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
NFE2
Nearest miRNA
hsa-mir-1244-3/Upstream/68520; hsa-let-7i/Downstream/37220;
Nearest TSS
ENST00000382841/Upstream/2112; ENST00000553009/Downstream/1019;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/18792, chr12-CpG: 18/Downstream/69277
Upstream sequence
AGATTAGGGAGAACTCCCGAagagagagagacacacagagatgagacagaatgaaggggaaaaaaaggagggagagagaTTTAAGCATAGTGAGCTCAGT
Downstream sequence
GCCCTAGGGACATGCATGACTCAAACAAATGTGTGAGAACAAAGAAGAGGGGGACGAGTTTCTGCTATTGTGTCACTTCATCCCTGGACCCCAAACTCCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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