Basic Information
VIS ID
TVIS44026809
Fusion event
HTLV-1-GLS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
56875984/56482200 (Hg38)
End
56875984/56482200 (Hg38)
Orient
-
Location type
Intronic
Target gene
GLS2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/2144886; hsa-let-7i/Downstream/712304;
Nearest TSS
ENST00000382841/Upstream/1742; ENST00000639027/Downstream/5399;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/13556, chr12-CpG: 93/Downstream/5417
Nearest cancer related gene
GLS2(TSG, No orient, 0)
Upstream sequence
ggcttctgtaatctcagctacttgggaagctgaggcaggagaattgcctgagcctgggaggtggaggttatagtcagtcgagattgtgccactgcactcc
Downstream sequence
agcctgggtgacagagtgagactttgtttaaaaaaaaaataaagtaaaataaataaaacctgcccacttaactttcctattccccatcatgcccacactc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate