Basic Information
VIS ID
TVIS44026811
Fusion event
HTLV-1-TSPAN31 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
58140340/57746557 (Hg38)
End
58140340/57746557 (Hg38)
Orient
+
Location type
Intronic
Target gene
TSPAN31
miRNAs that regulate target gene
hsa-mir-1247-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-3612 ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4325 ; hsa-mir-4537 ; hsa-mir-4746-3p ; hsa-mir-4792 ; hsa-mir-5694 ; hsa-mir-6086 ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-7703 ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-1183 ; hsa-mir-1208 ; hsa-mir-1304-3p ; hsa-mir-143-5p ; hsa-mir-3136-3p ; hsa-mir-3137 ; hsa-mir-3677-5p ; hsa-mir-4275 ; hsa-mir-504-3p ; hsa-mir-5693 ; hsa-mir-5698 ; hsa-mir-6499-3p ; hsa-mir-6504-3p ; hsa-mir-663b ; hsa-mir-6760-3p ; hsa-mir-6819-3p ; hsa-mir-6877-3p ; hsa-mir-7155-3p
Nearest miRNA
hsa-mir-1228/Upstream/227298; hsa-let-7i/Downstream/2061;
Nearest TSS
ENST00000382841/Upstream/1100; ENST00000546922/Downstream/110;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/7606, chr12-CpG: 45/Downstream/5513
Upstream sequence
TATCGTGTCTATAATTGTTGCACACCGTTATGCTTCTGTTTGACTTCCTTTGCTGGGCTAGGGAAATTGAGGCACTTGAACTGATAACAGGATGTAGGGA
Downstream sequence
GACTTAATTTCCCTCTACCCATATCTTTCAGACAGATGTCATCAATGCTTCTTGGTGGGTCATGAGCAACAAGACTCGGGATGAACTGGAAAGAAGTTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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