Basic Information
VIS ID
TVIS44026845
Fusion event
HTLV-1-E2F7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
77446555/77052775 (Hg38)
End
77446555/77052775 (Hg38)
Orient
+
Location type
Intronic
Target gene
E2F7
miRNAs that regulate target gene
hsa-mir-26a-5p ; hsa-mir-125a-5p ; hsa-mir-9-5p ; hsa-mir-128-3p ; hsa-mir-10a-5p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-125b-5p ; hsa-let-7b-5p ; hsa-mir-4282 ; hsa-mir-6798-3p ; hsa-mir-95-5p ; hsa-mir-3163 ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-548at-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-6792-5p ; hsa-mir-548e-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-15b-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-1297 ; hsa-mir-3144-3p ; hsa-mir-376a-5p ; hsa-mir-376a-2-5p ; hsa-mir-643 ; hsa-mir-4431 ; hsa-mir-5697 ; hsa-mir-6831-5p ; hsa-mir-4640-3p ; hsa-mir-3927-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p
Nearest miRNA
hsa-let-7i/Upstream/7467952; hsa-mir-1178/Downstream/2366482;
Nearest TSS
ENST00000382841/Upstream/2029; ENST00000552736/Downstream/12775;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/173339, chr12-CpG: 91/Downstream/12392
Upstream sequence
aatgaactatattaaacttaagaacttttgtccatcaagaaataacataaagggaaaagacaattaccgaactgaaagaatagatacataacatatataa
Downstream sequence
taaaggtttagtatcattatataatcaacccctacaaatcaacatgacaaaaaaaaaccaattaaaattggcaaagaacacaaacaggcatttcacagag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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