Basic Information
VIS ID
TVIS44026847
Fusion event
HTLV-1-OTOGL integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
80700758/80306978 (Hg38)
End
80700758/80306978 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
OTOGL
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7i/Upstream/887657; hsa-mir-1178/Downstream/525555;
Nearest TSS
ENST00000382841/Upstream/97525; ENST00000550182/Downstream/29534;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/371456, chr12-CpG: 50/Downstream/401277
Upstream sequence
caatagtggagggaaggtcagcagataaacaagtgaacaaaggtctctggttttcctaggcagaggaccctgcggcctttccgcagtgtttgtgtccctg
Downstream sequence
attacttgagattagggagtggtgatgactcttaacgagcatgctgccttcaagcatctgtttaacaaagcacatcttgcaccgcccttaatccattcaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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