Basic Information
VIS ID
TVIS44026849
Fusion event
HTLV-1-PTPRQ integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
80943670/80549891 (Hg38)
End
80943670/80549891 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
PTPRQ
Nearest miRNA
hsa-let-7i/Upstream/1130570; hsa-mir-1178/Downstream/282642;
Nearest TSS
ENST00000382841/Upstream/7635; ENST00000549355/Downstream/43810;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/614369, chr12-CpG: 50/Downstream/158364
Upstream sequence
CAATACCACCTGCAATCTTTATAGCATACTTATCTAAACATACAAAGCACATATTAAAAAATACAACACAGGCTTTTTATCCCACGTGTTGCTTGAGTAC
Downstream sequence
CAGCTGTGTACTACATTGACCCTTCTCCAAAACATTGGGAGATTGAAGGGAGGAAAAAAAGAGAGATGATCCTCTTTACTGTATTTCCACAAATATAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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