Basic Information
VIS ID
TVIS44026854
Fusion event
HTLV-1-AICDA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
8760715/8608119 (Hg38)
End
8760715/8608119 (Hg38)
Orient
-
Location type
Intronic
Target gene
AICDA
miRNAs that regulate target gene
hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p
Nearest miRNA
hsa-mir-141/Upstream/1643928; hsa-let-7i/Downstream/631348;
Nearest TSS
ENST00000382841/Upstream/1103; ENST00000539089/Downstream/4682;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2636, chr12-CpG: 150/Downstream/89337
Upstream sequence
caggctccgcggatcctcctgcctcagcctcctgagtagctgggattacaggcgcccaccatcatgcccaggtaatgtttgtatttttaatagagacggg
Downstream sequence
gtttcaccatcttggccaggctggccttggactcctgacctcgggtgttctgcccgccttggcttcccaaagtgctgggattacaggcgtgagccactgc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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