Basic Information
VIS ID
TVIS44026867
Fusion event
HTLV-1-FGD6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
GRCh37/hg19
Start
95559395/95165619 (Hg38)
End
95559395/95165619 (Hg38)
Orient
+
Location type
Intronic
Target gene
FGD6
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-6807-5p ; hsa-mir-135b-3p ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-508-3p ; hsa-mir-5186 ; hsa-mir-186-3p ; hsa-mir-4698 ; hsa-mir-150-5p ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-1292-5p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-3918 ; hsa-mir-802 ; hsa-mir-8083 ; hsa-mir-6753-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-6514-5p ; hsa-mir-3692-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u
Nearest miRNA
hsa-let-7i/Upstream/331106; hsa-mir-1178/Downstream/142801;
Nearest TSS
ENST00000382841/Upstream/48646; ENST00000551792/Downstream/43337;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/91931, chr12-CpG: 118/Downstream/51439
Upstream sequence
agacaggttggtttctccatggtggtcaggctggtctcgaactcccgacctcaggtgatccgccagcctcagcctcccaaagtgctaagattacaggcat
Downstream sequence
gagccaccgcgcccggccAAttttgttttttcctaagtgagatgaggcctccctgttgcccaggctggaatgctgtggcatgacctccactcactgcaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate