VISDB Viral Integration Site DataBase

VIS ID

TVIS44026871

Fusion event

HTLV-1-APAF1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Not given

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

q23.1

Reference genome

Start

End

99058395/98664617 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-624-3p ; hsa-mir-221-3p ; hsa-mir-23a-3p ; hsa-mir-4294 ; hsa-mir-1273e ; hsa-mir-6894-5p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-7162-3p ; hsa-mir-4649-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-4435 ; hsa-mir-2861 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-564 ; hsa-mir-4755-3p ; hsa-mir-3179 ; hsa-mir-3190-5p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-3622a-5p ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-6771-5p ; hsa-mir-7977 ; hsa-mir-933 ; hsa-mir-7160-5p ; hsa-mir-219b-3p ; hsa-mir-20b-3p ; hsa-mir-6746-5p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-1228-3p ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-302f ; hsa-mir-26a-1-3p ; hsa-mir-23a-5p ; hsa-mir-34a-5p

Nearest miRNA

hsa-let-7i/Upstream/669169; hsa-mir-1178/Downstream/1525267;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/18912, chr12-CpG: 42/Downstream/80991

Nearest cancer related gene

APAF1(TSG, No orient, 0)

Upstream sequence

tatatgtggttttggattttgcccttttttttttaaagagccagggtcttgctctgtcacccaggctggagtgcagtaagatcacagctcactgcaggct

Downstream sequence

tgaatgtcttggcttaagcaatcctcctgccccagcctcctgaatagctgggactgcagatacccaccaccacacctgggtaatttttaaatttttttgt