Basic Information
VIS ID
TVIS44026872
Fusion event
HTLV-1-PCCA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
100962839/100310585 (Hg38)
End
100962839/100310585 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
PCCA
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-455-5p ; hsa-mir-7152-5p ; hsa-mir-568 ; hsa-mir-1273e ; hsa-mir-155-5p ; hsa-mir-4326 ; hsa-mir-15b-3p ; hsa-mir-486-5p
Nearest miRNA
hsa-mir-1297/Upstream/667436; hsa-mir-1267/Downstream/1657057;
Nearest TSS
ENST00000623511/Upstream/4809; ENST00000413170/Downstream/57887;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/221034, chr13-CpG: 51/Downstream/221557
Upstream sequence
AATATTTTGTCAAAACTCATTTCTGTTAAACTGTGATATAATACGACATAGGGGCATGGCATCTGGGCAGTTTGTCAAAATATTAGATTAGTTTTGGTCC
Downstream sequence
CAACTAGAAGTTATTTATCTACTCCATCTGGCTTCTGAAAGGAGTACTCTTTTGTATTTACATGAATACCATTTCATGTTTTATACTTAAATGAACATTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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