Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene100699564100603927100675093100530164100589528100608192100610998100587912100589416100600627100601717100612116100612840100573147100573296100583894100583953100614864
Basic Information
VIS ID
TVIS44026873
Fusion event
HTLV-1-TMTC4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
101267118/100614864 (Hg38)
End
101267118/100614864 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
TMTC4
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-24-3p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1297/Upstream/971715; hsa-mir-1267/Downstream/1352778;
Nearest TSS
ENST00000623511/Upstream/25336; ENST00000457843/Downstream/21744;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/25892, chr13-CpG: 177/Downstream/59211
Upstream sequence
GTGATTTTAGGAATCAAATCATATTTCAGACTGCTGAAATACTGAAGAAAGCCTCATCATTAGTCTTTTTCACTAAAGACTTCATAAGTTCATTGTTGAT
Downstream sequence
AAAGTATTACTTAGAATAGTGAACAAAGTATTTCTCATGATCAAAAGCTATGTGTCCAATTCACCTTGTGAAGGGTGGTCTCAGGGCCTCTTCCTGCCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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