Basic Information
VIS ID
TVIS44026890
Fusion event
HTLV-1-TUBGCP3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
113199225/112544911 (Hg38)
End
113199225/112544911 (Hg38)
Orient
+
Location type
Intronic
Target gene
TUBGCP3
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-18a-3p ; hsa-let-7b-5p ; hsa-mir-668-3p ; hsa-mir-483-3p ; hsa-mir-4699-3p
Nearest miRNA
hsa-mir-1267/Upstream/2203882; hsa-mir-4502/Downstream/718009;
Nearest TSS
ENST00000623511/Upstream/55088; ENST00000623100/Downstream/1292;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/58898, chr13-CpG: 28/Downstream/2481
Upstream sequence
ccaaacgcttgctttaaaaacaacttgtaacagcacaaacaataaattagaaaacaaattgaatgtaatacaaacctcacgcttgcttatttgcaatttc
Downstream sequence
atccatgagaaacggcaggagaacacaggccactgcagccagcAGCGCCCACACAAGGCACACCTGtttcagatggccaggcctccgccacttcccgcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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