Basic Information
VIS ID
TVIS44026893
Fusion event
HTLV-1-ATP11A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
113486477/112832163 (Hg38)
End
113486477/112832163 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATP11A
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-769-5p ; hsa-mir-484 ; hsa-mir-197-3p ; hsa-mir-92a-3p ; hsa-mir-4777-5p ; hsa-mir-523-5p ; hsa-mir-526a ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-337-3p ; hsa-mir-202-5p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-617 ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-211-3p ; hsa-mir-5680 ; hsa-mir-3121-3p
Nearest miRNA
hsa-mir-1267/Upstream/2491134; hsa-mir-4502/Downstream/430757;
Nearest TSS
ENST00000623511/Upstream/46991; ENST00000459011/Downstream/4080;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/12125, chr13-CpG: 38/Downstream/358
Upstream sequence
ctcacatgcagacacacacgtactctcacacacgcccagttaccgtgtgcacgcacagacacatgctcacacgcagacacacacatgcactctcacacac
Downstream sequence
gcCCCAAATGCCGTGGCTCCAGATCTCAGCATCTCTGGGCAGGGCTGAAGTCCCAGGCTGATGCTGTTCCTGAATTTCCCCGCACACAGGGCAGCCTCGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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