Basic Information
VIS ID
TVIS44026895
Fusion event
HTLV-1-DCUN1D2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
114127074/113472759 (Hg38)
End
114127074/113472759 (Hg38)
Orient
-
Location type
Intronic
Target gene
DCUN1D2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-191-5p ; hsa-mir-373-5p ; hsa-mir-616-5p ; hsa-mir-371b-5p ; hsa-mir-1228-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-6778-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-6747-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p
Nearest miRNA
hsa-mir-1267/Upstream/209760; hsa-mir-4502/Downstream/771746;
Nearest TSS
ENST00000623511/Upstream/3858; ENST00000453584/Downstream/2631;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/30757, chr13-CpG: 135/Downstream/17404
Upstream sequence
GGATCATCCCAGCTCACAAACAGAAAGGGCAGGACAGGCTCTCATCAGTTGGCAGCCCTGAGCAAGGCTGGAGGTCTCGACACTGCTGGTGTCCCTAGGT
Downstream sequence
GCCGCATGCGGCAGGCTCCTGAGCCAAGACGCAGCAGACACCGCTACTGTCACCCAAGAGGCAAAGCGAGGGCCCAACAGGCCCCAGGGCCTTGCACAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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