Basic Information
VIS ID
TVIS44026903
Fusion event
HTLV-1-LATS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q12.11
Reference genome
GRCh37/hg19
Start
21562893/20988754 (Hg38)
End
21562893/20988754 (Hg38)
Orient
-
Location type
Exonic
Target gene
LATS2
miRNAs that regulate target gene
hsa-mir-31-5p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-93-5p ; hsa-mir-181b-5p ; hsa-mir-135b-3p ; hsa-mir-107 ; hsa-mir-25-3p ; hsa-mir-223-3p ; hsa-mir-6801-5p ; hsa-mir-4697-3p ; hsa-mir-1256 ; hsa-mir-202-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-545-5p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-183-5p ; hsa-mir-1182 ; hsa-mir-1178-5p ; hsa-mir-562 ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-548m ; hsa-mir-510-3p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-494-3p ; hsa-mir-574-5p ; hsa-mir-4789-5p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-181c-5p ; hsa-mir-3605-3p ; hsa-mir-3659 ; hsa-mir-4468 ; hsa-mir-759 ; hsa-mir-802
Nearest miRNA
hsa-mir-4499/Upstream/554908; hsa-mir-1267/Downstream/3173662;
Nearest TSS
ENST00000623511/Upstream/85706; ENST00000422510/Downstream/16403;
Nearest CpG islands
chr13-CpG: 115/Target, None/Upstream, None/Downstream
Nearest cancer related gene
LATS2(TSG, No orient, 0)
Upstream sequence
CAGGGTGGCAGCCGGCCACTGCTGGACGGAGGTGCTGCCCAATTCATACAGGTCCACGTTGAGGCTGTTCCGCGAGGGAGTGAGCAGGCTCTGCGGGGGG
Downstream sequence
CTGTCGCTGGCGAACACCTGGCTGCGGGAGCCCAGCACATGCAGCTGGTGGGCCGCGGGACCGGCCTGCTTGTGGTGTGGGTGCGGCACGTAGAGCCCGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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