Basic Information
VIS ID
TVIS44026935
Fusion event
HTLV-1-VWA8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
42416643/41842507 (Hg38)
End
42416643/41842507 (Hg38)
Orient
-
Location type
Intronic
Target gene
VWA8
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-1229-3p ; hsa-mir-1227-3p
Nearest miRNA
hsa-mir-2276/Upstream/274112; hsa-mir-1267/Downstream/2353622;
Nearest TSS
ENST00000623511/Upstream/146388; ENST00000612345/Downstream/25896;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/383976, chr13-CpG: 71/Downstream/118237
Upstream sequence
CTTTTATGTACAGGATGCGATGTTGACATTACAAGCCTACTATGTTGATTTCAGTTACTCTGCTGTCAATGGGGAAAAGTTGATTTTGCAGTTGTATGTG
Downstream sequence
TGGTAAGCACTGGAATCTATTTCAAGATGATCTGCTTTAGTTAAAGATTTATACTATGAACACAGAATAAATTTCTCTCATTGAAGATAACCAGAAGTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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