Basic Information
VIS ID
TVIS44026938
Fusion event
HTLV-1-TSC22D1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
45103892/44529756 (Hg38)
End
45103892/44529756 (Hg38)
Orient
+
Location type
Intronic
Target gene
TSC22D1
miRNAs that regulate target gene
hsa-mir-100-5p ; hsa-mir-9-3p ; hsa-mir-590-3p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-1825 ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-6758-5p ; hsa-mir-6856-5p
Nearest miRNA
hsa-mir-2276/Upstream/333556; hsa-mir-1267/Downstream/5466659;
Nearest TSS
ENST00000623511/Upstream/55455; ENST00000617014/Downstream/10277;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/92497, chr13-CpG: 216/Downstream/46173
Nearest cancer related gene
TSC22D1(TSG, No orient, 0)
Upstream sequence
atgatatgattgtgtatgttgaaaaccgcaaggaatcaaggaaaagattcctgcaactaacacctatagcaaggttgaagaatataaggttagtacacaa
Downstream sequence
gtcaattgctttcccatacaccagcaatgaacaattggaattggaaattaaaacaccatttacattaacaccaagaaattaaacactttggtataaatct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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