Basic Information
VIS ID
TVIS44026947
Fusion event
HTLV-1-CKAP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
53040772/52466637 (Hg38)
End
53040772/52466637 (Hg38)
Orient
+
Location type
Intronic
Target gene
CKAP2
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-222-3p ; hsa-mir-106a-5p ; hsa-let-7b-5p ; hsa-mir-6755-5p ; hsa-mir-649 ; hsa-mir-490-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-548ah-5p ; hsa-mir-3609
Nearest miRNA
hsa-mir-15a/Upstream/913970; hsa-mir-1267/Downstream/343413;
Nearest TSS
ENST00000623511/Upstream/10629; ENST00000459902/Downstream/6898;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/10644, chr13-CpG: 29/Downstream/22262
Upstream sequence
TATCAGAAGGGACATTACTTAAGGCAGCTAAGGACATTGTAGCAAGGATGCAAAACTGGAGCCAAGGCTCACATAGAAAGCAATAATGTAAACAGCAAGA
Downstream sequence
TGTAACACCAGAGGAAAAGCTGCTGGAAAACAAGAATCAAAATTAGCCAACATGgctgggcacagtagtggatacctatagtctcaactacttgggaggc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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