Basic Information
VIS ID
TVIS44027001
Fusion event
HTLV-1-GPC6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
94609640/93957387 (Hg38)
End
94609640/93957387 (Hg38)
Orient
-
Location type
Intronic
Target gene
GPC6
miRNAs that regulate target gene
hsa-mir-361-5p ; hsa-mir-1279 ; hsa-mir-483-5p ; hsa-mir-32-3p ; hsa-mir-7161-5p ; hsa-mir-548u
Nearest miRNA
hsa-mir-1297/Upstream/1467167; hsa-mir-1267/Downstream/2469842;
Nearest TSS
ENST00000623511/Upstream/121243; ENST00000617456/Downstream/230604;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/728763, chr13-CpG: 59/Downstream/591919
Upstream sequence
acacgtacaggcttgttacatgggtgtattatatgcagttcatgagcgtagtatcaaataagtagtttttgaacccatgctcccttcctgtcatccccct
Downstream sequence
ccactagtcggcagtgaccattgttcccgtaattatgtccatgtgtgcccaatgtttagctccctcttataagtgagaacatgaggtatttggctttctg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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