Basic Information
VIS ID
TVIS44027006
Fusion event
HTLV-1-HS6ST3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
96761229/96108975 (Hg38)
End
96761229/96108975 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
HS6ST3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-5589-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-574-5p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-592 ; hsa-mir-513a-5p ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-597-5p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-4445-5p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-6767-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485
Nearest miRNA
hsa-mir-1297/Upstream/3618755; hsa-mir-1267/Downstream/318254;
Nearest TSS
ENST00000623511/Upstream/18136; ENST00000620595/Downstream/723513;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/17067, chr13-CpG: 35/Downstream/885165
Upstream sequence
GGTGCATGGGAACTCCAGGACAGTAAGGAGGTCACAGGGCAGCATTCCATGAAAGGTTAAATCTGTGACAACCACTCctatctctatctctatctctatc
Downstream sequence
tctatctctatctctatctctatccctCTATCATCTGGATCTTTATATTGTAACTATGTTTATGTTTAACTCTATCATAGTTAGCAAGAAATGGTTAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate