Basic Information
VIS ID
TVIS44027015
Fusion event
HTLV-1-PPP1R13B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
104218097/103751760 (Hg38)
End
104218097/103751760 (Hg38)
Orient
-
Location type
Intronic
Target gene
PPP1R13B
miRNAs that regulate target gene
hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-93-3p ; hsa-mir-766-3p ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-138-5p ; hsa-mir-10b-5p
Nearest miRNA
hsa-mir-1185-1/Upstream/1212034; hsa-mir-12121/Downstream/365645;
Nearest TSS
ENST00000550708/Upstream/4363; ENST00000556586/Downstream/88347;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/12768, chr14-CpG: 218/Downstream/95064
Upstream sequence
cacggagagagactacaactctctctccactacgtggggacacagcgagaaggcggctctctgcaagccagggagtgaacattcactggaaactgaattt
Downstream sequence
gctggcaccttgatcttggacttccagcctccagaacagtgggaaataaatgtctatagtttaagccatccagcctatgatattttgttatagcagtctg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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