Basic Information
VIS ID
TVIS44027030
Fusion event
HTLV-1-IPO4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
24651330/24182124 (Hg38)
End
24651330/24182124 (Hg38)
Orient
-
Location type
Exonic
Target gene
IPO4
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-940 ; hsa-mir-877-3p ; hsa-mir-193b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-208a/Upstream/38559; hsa-mir-1185-1/Downstream/2726518;
Nearest TSS
ENST00000550708/Upstream/2596; ENST00000610486/Downstream/1148;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/9113, chr14-CpG: 60/Downstream/6233
Upstream sequence
GGTCTGCCTCTTGGGCGGTGCTCAACAGCACAGGGAGCAGCCGAGACACAAACTGGGCTGAGGCAGCACCCAGGCCCTGAATAGTCTCTGCCAAGGTCCC
Downstream sequence
CACTGCAAAGGACTTCTCTGCCACTGTGCAGCCCTGTTTCTGATGGGGGAGAACAGGAAGGAGTACAGATCAGCCTGGGCCAAGGATAAAGGCTGTGGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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