Basic Information
VIS ID
TVIS44027032
Fusion event
HTLV-1-STXBP6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
25445683/24976477 (Hg38)
End
25445683/24976477 (Hg38)
Orient
-
Location type
Intronic
Target gene
STXBP6
miRNAs that regulate target gene
hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-4539
Nearest miRNA
hsa-mir-208a/Upstream/832912; hsa-mir-1185-1/Downstream/1932165;
Nearest TSS
ENST00000550708/Upstream/157000; ENST00000547786/Downstream/34163;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/546305, chr14-CpG: 125/Downstream/72741
Upstream sequence
CAGGTTTTCTTAGTGACACAAGAATACCTATCTATACATACACAAAGAATATGTATCTAGATATCCTAGAAATTATAGATCTAATACCCACATCTACTTG
Downstream sequence
TGCTCCAATCCCAACATTTTATCATCACCACCAGGTTCTTCATGCTGGCCAAGAACAAAATGACAACAGTGGAGGGGGACCTGTTTTTCAAATGCTGATC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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