Basic Information
VIS ID
TVIS44027043
Fusion event
HTLV-1-ARHGAP5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
32547657/32078451 (Hg38)
End
32547657/32078451 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGAP5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-486-5p ; hsa-mir-494-3p ; hsa-mir-770-5p ; hsa-mir-493-5p ; hsa-mir-493-3p ; hsa-mir-744-5p
Nearest miRNA
hsa-mir-208a/Upstream/1063709; hsa-mir-1185-1/Downstream/4873858;
Nearest TSS
ENST00000550708/Upstream/220; ENST00000557643/Downstream/15587;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/516, chr14-CpG: 53/Downstream/122760
Upstream sequence
AGACGCTTATACTTCTACCATGTGATAGAAATTCGGATTTGGCCATCGCTTAATAAATGGGAATTCAAATATTTTGAGATAGAGCAAGATAGGCATATAG
Downstream sequence
ATGGGTTTGTGCTTACGTTTTAAGTTTAAATTCTTATCGATCATTTATTTTTTCCTTTGTGATAGGCAGGAAACTGAATTTTTTTTTAAATGTTCAGGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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