Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene5606401056117814563015265617067256173807561331385613517456155967561573425613209956133002561678645616874356181459561822895614179156142607561374015613820056149787561505745616020056160400561766635617681256182768
Basic Information
VIS ID
TVIS44027085
Fusion event
HTLV-1-PELI2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
56649486/56182768 (Hg38)
End
56649486/56182768 (Hg38)
Orient
-
Location type
Intronic
Target gene
PELI2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-151a-5p ; hsa-mir-222-3p ; hsa-mir-498 ; hsa-mir-377-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-34b-3p
Nearest miRNA
hsa-mir-208a/Upstream/1304575; hsa-mir-1185-1/Downstream/3464194;
Nearest TSS
ENST00000550708/Upstream/63659; ENST00000612106/Downstream/123070;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/63252, chr14-CpG: 41/Downstream/396986
Upstream sequence
TTTAATGTCATTGCTACAACCAggctgctcttcaccgtgtttgggctgctgtggctctactggttgataaaatattgaaacactttcttatcagttgatg
Downstream sequence
aataATACAACAGTAACCGTGAGAAGTGGTAAAACTAACAATATAATTTTCAACATAAACTCATTCACCCTAGCTGATTTTGTAGGATGTGCTGGGGTCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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