Basic Information
VIS ID
TVIS44027095
Fusion event
HTLV-1-MNAT1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
61380267/60913549 (Hg38)
End
61380267/60913549 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
MNAT1
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-208a/Upstream/264838; hsa-mir-1185-1/Downstream/3181475;
Nearest TSS
ENST00000550708/Upstream/101562; ENST00000525585/Downstream/67502;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/189495, chr14-CpG: 45/Downstream/67396
Nearest cancer related gene
MNAT1(OG, No orient, 0)
Upstream sequence
ttgtggttttatctaccttgggtctttgatgatggtggcgtccagatgggtttttggtgtggatggcctttctgttttttagttttccttctaacagtca
Downstream sequence
ggaccctcagctgcaggtctgttggagtttactggaggtccactccagacccggtttgcctgggtatcagcaggggaggctgcagaacagtggatattgg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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