Basic Information
VIS ID
TVIS44027106
Fusion event
HTLV-1-GPHN integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
67302319/66835601 (Hg38)
End
67302319/66835601 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
GPHN
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-375
Nearest miRNA
hsa-mir-208a/Upstream/1364415; hsa-mir-1185-1/Downstream/606254;
Nearest TSS
ENST00000550708/Upstream/11127; ENST00000556501/Downstream/134215;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/326084, chr14-CpG: 95/Downstream/405435
Upstream sequence
aaaaactggaagcattccctttgaaaactggcacaagacagggatgccctctctcaccactcctattcaacatagtgttggaagttctggccagggcaat
Downstream sequence
taggcaggagaaggaaataaagggtattcaattaggaaaagaggaagtcaaattgtccgtgtctgcagatgacatgattgtatatctagaaaaccccatt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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