Basic Information
VIS ID
TVIS44027109
Fusion event
HTLV-1-RAD51B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
69053735/68587018 (Hg38)
End
69053735/68587018 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14C
Target gene
RAD51B
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-4668-5p ; hsa-mir-2053 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-30b-3p ; hsa-mir-3689a-3p ; hsa-mir-1273h-5p ; hsa-mir-569 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-766-5p ; hsa-mir-6871-5p ; hsa-mir-4496 ; hsa-mir-4506
Nearest miRNA
hsa-mir-208a/Upstream/1145088; hsa-mir-1185-1/Downstream/3929802;
Nearest TSS
ENST00000550708/Upstream/41456; ENST00000553944/Downstream/41427;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/911853, chr14-CpG: 40/Downstream/41280
Upstream sequence
cacttgaacctaggaggcagaggttgcagtgagtcgagatcacgccattgcagtgagccgagatcgcgccattgtactccagccaacaagagcaaaactc
Downstream sequence
tgtctcaaaaaaaaaaaaaaTTGGCTCCTTCCAGctttgagatcctgaggccagcagccagggatcctgctctctgctatatgtcagtgttccagcacag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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