Basic Information
VIS ID
TVIS44027116
Fusion event
HTLV-1-ACYP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
75526675/75059972 (Hg38)
End
75526675/75059972 (Hg38)
Orient
+
Location type
Intronic
Target gene
ACYP1
miRNAs that regulate target gene
hsa-mir-374a-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p
Nearest miRNA
hsa-mir-208a/Upstream/579768; hsa-mir-1185-1/Downstream/2206246;
Nearest TSS
ENST00000550708/Upstream/8440; ENST00000525046/Downstream/4035;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/8451, chr14-CpG: 53/Downstream/9150
Upstream sequence
tactgtaaaattccacttatatgaggtaactagagcagttgaattaatagaatgtagatttatgattgtcaggggcatgggggaaggagaaaatggggag
Downstream sequence
ttagtgtttaatgaatacagagtttcagttttgcaagatgaaaagcgttctgtagataaacagaacaatgtgaatgtgcttaagaccactgaattgtaca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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