Basic Information
VIS ID
TVIS44027145
Fusion event
HTLV-1-ITPK1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
93418599/92952254 (Hg38)
End
93418599/92952254 (Hg38)
Orient
-
Location type
Intronic
Target gene
ITPK1
miRNAs that regulate target gene
hsa-mir-421 ; hsa-mir-218-5p ; hsa-mir-6744-5p ; hsa-mir-4537 ; hsa-mir-6872-3p ; hsa-mir-6746-3p
Nearest miRNA
hsa-mir-1260a/Upstream/15685964; hsa-mir-1185-1/Downstream/995972;
Nearest TSS
ENST00000550708/Upstream/20577; ENST00000553639/Downstream/46685;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/28700, chr14-CpG: 44/Downstream/106168
Upstream sequence
TGGGCACCAGCCCTGGGCACGGATGTGTGCCCCATCAGGGCTCCGGTTCACCTTCTCCTCCCACATAAAAGTAACCGATGTAATGAGCTGACCTCTGCTA
Downstream sequence
CCATCTCACAGCATCACATCTGGTTTTCCCTGAGGCCCTGTTCCCAAAGTGTGCTGTCACTATACAGGGAAGTAGGGGAAAAGGGCTCGGTGGGACAGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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