Basic Information
VIS ID
TVIS44027147
Fusion event
HTLV-1-ASB2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
94419913/93953567 (Hg38)
End
94419913/93953567 (Hg38)
Orient
+
Location type
Intronic
Target gene
ASB2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-7-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1260a/Upstream/5265; hsa-mir-1185-1/Downstream/1184352;
Nearest TSS
ENST00000550708/Upstream/13072; ENST00000449472/Downstream/1704;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/13743, chr14-CpG: 77/Downstream/72726
Upstream sequence
TCCTCCTGCAGGGTGCGCTGGTCGATGGTCCCTGGGTACGCTAGGGAGGGCCCACCGGGAAATTCATGTAGGAGAAAGATACTCAGCCCCGCAACACAGA
Downstream sequence
GGCTTTCCCGATTGCCTCCCAATTTCAAGAACAATGTATGACATCCTCTGAAATTTACCAACTACAGACTGCATTCATCTGGCcctttcacagggccatt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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