Basic Information
VIS ID
TVIS44027148
Fusion event
HTLV-1-DDX24 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
94534015/94067669 (Hg38)
End
94534015/94067669 (Hg38)
Orient
+
Location type
Intronic
Target gene
DDX24
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-744-5p ; hsa-mir-505-5p ; hsa-mir-423-5p ; hsa-mir-769-5p
Nearest miRNA
hsa-mir-1260a/Upstream/119367; hsa-mir-1185-1/Downstream/1070250;
Nearest TSS
ENST00000550708/Upstream/5416; ENST00000555065/Downstream/13477;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/40718, chr14-CpG: 70/Downstream/12986
Upstream sequence
aagagctgtgagacagaagcaccagataacctataaaggaaaacctatcagattaacagtagacatctcaggagaaaccctacaagctagaagggactgg
Downstream sequence
ggccctatcttcaacctcctcaaacaaaacaatcttcagccaagaattttgtatccagcaaaactaagcatcatatatgaaggaaagatacaattgtttt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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