Basic Information
VIS ID
TVIS44027157
Fusion event
HTLV-1-CCDC85C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
99998426/99532089 (Hg38)
End
99998426/99532089 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC85C
miRNAs that regulate target gene
hsa-mir-670-3p ; hsa-mir-1238-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-3119 ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-432-3p ; hsa-mir-1193 ; hsa-mir-6760-5p ; hsa-mir-5195-3p ; hsa-mir-145-5p
Nearest miRNA
hsa-mir-1260a/Upstream/4394103; hsa-mir-1185-1/Downstream/577330;
Nearest TSS
ENST00000550708/Upstream/9144; ENST00000502101/Downstream/3999;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/50238, chr14-CpG: 287/Downstream/71049
Upstream sequence
TTGGCCGTGGAGACTGGACAGGGATCAGCCACAGGCTCCCCAAGACACATCCACCCAGTTCAACCATGCTGAGCACTGGAGACACCAATGTGGCCACTCA
Downstream sequence
GACCCTGCAGCCCTGTCCTGGAGAAGATGACAGTCCCACAGGGGTGGGGGCCAGGATCCACAAGGGTGGGTCATGACACCCTATCAGCAAAGGTGGGCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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