Basic Information
VIS ID
TVIS44027190
Fusion event
HTLV-1-GATM integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
45693879/45401681 (Hg38)
End
45693879/45401681 (Hg38)
Orient
-
Location type
Intronic
Target gene
GATM
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4263 ; hsa-mir-297 ; hsa-mir-6873-3p ; hsa-mir-6830-3p ; hsa-mir-567 ; hsa-mir-6845-3p ; hsa-mir-1264 ; hsa-mir-3184-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-126-5p ; hsa-mir-3677-5p ; hsa-mir-3926 ; hsa-mir-3927-3p ; hsa-mir-4257 ; hsa-mir-4458 ; hsa-mir-4460 ; hsa-mir-4480 ; hsa-mir-4500 ; hsa-mir-4727-3p ; hsa-mir-548ac ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-548bb-3p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548j-3p ; hsa-mir-548s ; hsa-mir-548x-3p ; hsa-mir-548z ; hsa-mir-6831-5p ; hsa-mir-8069 ; hsa-mir-944 ; hsa-mir-98-5p
Nearest miRNA
hsa-mir-10393/Upstream/683788; hsa-mir-11181/Downstream/31369;
Nearest TSS
ENST00000557528/Upstream/4335; ENST00000525552/Downstream/537;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/22850, chr15-CpG: 156/Downstream/531
Nearby gene
SPATA5L1(+640) ;
Upstream sequence
AGCAGGCAGTTGTCTTAATAACGTAGATAGGTATCGCCTCTAATACAGGACTTAGTACTGTTGTGCCCCAATTAGACAGTAAGCATTGATCGCATGAACT
Downstream sequence
TTAGTGATTAACTTGTTGCCAAAGAATATTCAAAAGAATATCAGAAATCAGAACAAATGTACTGTTGGTGTGCTACAAATCCATCAGGTAGCCTAGTTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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