Basic Information
VIS ID
TVIS44027191
Fusion event
HTLV-1-BLOC1S6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
45882208/45590010 (Hg38)
End
45882208/45590010 (Hg38)
Orient
-
Location type
Intronic
Target gene
BLOC1S6
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-30b-5p ; hsa-mir-101-3p ; hsa-mir-484 ; hsa-mir-3176 ; hsa-mir-218-5p ; hsa-mir-222-5p ; hsa-mir-219a-2-3p ; hsa-mir-576-3p ; hsa-mir-936 ; hsa-mir-3123 ; hsa-mir-3925-5p ; hsa-mir-3935 ; hsa-mir-3976 ; hsa-mir-3977 ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-636 ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-873-5p ; hsa-mir-570-3p ; hsa-mir-3129-5p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-5683 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-1193 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-4781-3p ; hsa-mir-2392 ; hsa-mir-605-3p ; hsa-mir-627-3p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-186-5p ; hsa-mir-3133
Nearest miRNA
hsa-mir-10393/Upstream/156881; hsa-mir-11181/Downstream/3579060;
Nearest TSS
ENST00000557528/Upstream/2185; ENST00000564310/Downstream/2114;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/2290, chr15-CpG: 75/Downstream/44669
Upstream sequence
GGGAGGAGGGTTTGTGAGTTAAAATGTATGTATATATTGTTAAGCGAAGTGAATTAGTTGTTATTCCTTAAAGTTGAAATGCCCTTTTTTGGGGTGTTCC
Downstream sequence
TATCATAAAACATTAAGAAAATTGTTTTCTATATTTATTAATACTTAAAGTTGCTGATTGCATTGTTATTTTAATCAAGCCTTAAGCAACGGCATAATTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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