Basic Information
VIS ID
TVIS44027199
Fusion event
HTLV-1-SLC27A2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
50490076/50197879 (Hg38)
End
50490076/50197879 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC27A2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-let-7b-5p ; hsa-mir-6867-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6832-3p ; hsa-mir-3184-3p
Nearest miRNA
hsa-mir-10393/Upstream/1028726; hsa-mir-11181/Downstream/162450;
Nearest TSS
ENST00000557528/Upstream/6878; ENST00000559938/Downstream/7474;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/14890, chr15-CpG: 142/Downstream/156361
Upstream sequence
TCTCTTTCTTTGGCAAAACGTATTGGGTAACTAATACTTCAGGAGATTTAGTTATTTGCCTGCGGGAACTGATCTTATTTCATAGCATGTGATCCCATTT
Downstream sequence
GCGTTTCTCCAAGCTATGCATATTTTCCGCCAGTTGGTATAGAACAGATAAAGAGGTTAACCAAGAACTACAGAAGTAGTTATGATGATGAATGAGATTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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