Basic Information
VIS ID
TVIS44027202
Fusion event
HTLV-1-MNS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
56744270/56452072 (Hg38)
End
56744270/56452072 (Hg38)
Orient
+
Location type
Intronic
Target gene
MNS1
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-10393/Upstream/1079038; hsa-mir-11181/Downstream/2719111;
Nearest TSS
ENST00000557528/Upstream/4952; ENST00000621974/Downstream/13013;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/86387, chr15-CpG: 25/Downstream/12909
Upstream sequence
attctgatacaacatttcatcaattttggcaaatggttcaaatatgtttactataactactaatataattgggtttccatttacaagcttatatcttctt
Downstream sequence
tctacttgtcttccctgtcctatgttctctcttctctcctgtttgcttctgtgttgggggttcccaagaccaccatcaggttagatgattcactaggagg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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