Basic Information
VIS ID
TVIS44027209
Fusion event
HTLV-1-MYO1E integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
59641747/59349548 (Hg38)
End
59641747/59349548 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
MYO1E
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-30b-5p ; hsa-mir-93-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-10393/Upstream/178286; hsa-mir-11181/Downstream/2955110;
Nearest TSS
ENST00000557528/Upstream/84551; ENST00000558900/Downstream/22979;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/142409, chr15-CpG: 130/Downstream/22116
Upstream sequence
AGGGTAAACTGAACCCACTCTATTCAGAAAATTTCAACTCACAAACCTTCTTTAAATTACCCAGCGAGTTAGGGAGGAGGATGATGAGAAATCATCCTCA
Downstream sequence
TCCTTGCCAAGAATTTTTTCAAATAAGCAAACTATCCTGCCCAAATTCAGTGAATGCATTACTAATTAATTTCGTTCTGTGATGTCTGTTCTACATGATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate