Basic Information
VIS ID
TVIS44027210
Fusion event
HTLV-1-ANXA2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
60654022/60361823 (Hg38)
End
60654022/60361823 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
ANXA2
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-155-5p ; hsa-mir-769-3p ; hsa-mir-132-3p ; hsa-mir-133a-3p ; hsa-mir-218-5p ; hsa-mir-206
Nearest miRNA
hsa-mir-10393/Upstream/1190561; hsa-mir-11181/Downstream/1942835;
Nearest TSS
ENST00000557528/Upstream/10270; ENST00000501579/Downstream/12682;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/355502, chr15-CpG: 63/Downstream/35727
Upstream sequence
TTAAGGGTTGGATCCACTGTCACCATGAACACAAAAATTTGTCAGAGGTCTGGTCAGCACCCATGTATGTAGACAGACACCCCAACTCAATGTGTCTTTT
Downstream sequence
AGCGATGCTTCCTCGAGCTAAACTTCCTACAAATCATGGCTGATGACTGAAGCCTCCTACTGAAATAATGTtcttcttttcgcttttttttttttcttct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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