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TVIS44027213
Basic Information
VIS ID
TVIS44027213
Fusion event
HTLV-1-RORA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
61027137/60734938 (Hg38)
End
61027137/60734938 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
RORA
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-106b-5p
;
hsa-mir-92a-3p
;
hsa-mir-33b-5p
;
hsa-mir-129-5p
;
hsa-mir-32-3p
;
hsa-mir-1179
;
hsa-mir-374a-5p
;
hsa-mir-374b-5p
;
hsa-let-7f-2-3p
;
hsa-mir-1185-2-3p
;
hsa-mir-1185-1-3p
;
hsa-mir-153-5p
;
hsa-mir-1250-3p
;
hsa-let-7a-3p
;
hsa-let-7b-3p
;
hsa-let-7f-1-3p
;
hsa-mir-98-3p
;
hsa-mir-3611
;
hsa-mir-5580-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-670-3p
;
hsa-mir-4698
;
hsa-mir-548aw
;
hsa-mir-190a-3p
;
hsa-mir-1277-5p
;
hsa-mir-5011-5p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-3662
;
hsa-mir-942-5p
;
hsa-mir-506-5p
;
hsa-mir-137
;
hsa-mir-218-5p
;
hsa-mir-127-5p
;
hsa-mir-7843-3p
;
hsa-mir-4668-5p
;
hsa-mir-3613-5p
;
hsa-mir-4786-3p
;
hsa-mir-4635
;
hsa-mir-4781-3p
;
hsa-mir-4538
;
hsa-mir-4453
;
hsa-mir-7109-3p
;
hsa-mir-5010-3p
;
hsa-mir-2113
;
hsa-mir-758-3p
;
hsa-mir-1290
;
hsa-mir-876-5p
;
hsa-mir-3167
;
hsa-mir-3171
;
hsa-mir-873-5p
;
hsa-mir-1246
;
hsa-mir-8076
;
hsa-mir-144-3p
;
hsa-mir-101-3p
;
hsa-mir-4536-5p
;
hsa-mir-3924
;
hsa-mir-1277-3p
;
hsa-mir-4666a-3p
;
hsa-mir-381-3p
;
hsa-mir-300
;
hsa-mir-621
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-519e-3p
;
hsa-mir-515-3p
;
hsa-mir-33b-3p
;
hsa-mir-3646
;
hsa-mir-186-5p
;
hsa-mir-3133
;
hsa-mir-18a-5p
;
hsa-mir-4735-3p
;
hsa-mir-18b-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-526b-3p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-2054
;
hsa-mir-7848-3p
;
hsa-mir-4641
;
hsa-mir-656-3p
;
hsa-mir-504-5p
;
hsa-mir-10a-5p
;
hsa-mir-10b-5p
;
hsa-mir-155-5p
;
hsa-mir-4775
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-483-3p
;
hsa-mir-4725-5p
;
hsa-mir-4750-3p
;
hsa-mir-5685
;
hsa-mir-4690-3p
;
hsa-mir-6765-3p
;
hsa-mir-3622b-3p
;
hsa-mir-3622a-3p
;
hsa-mir-377-3p
;
hsa-mir-449c-3p
;
hsa-mir-6740-3p
;
hsa-mir-8086
;
hsa-mir-6870-3p
;
hsa-mir-622
;
hsa-mir-154-3p
;
hsa-mir-4643
;
hsa-mir-466
;
hsa-mir-4789-3p
;
hsa-mir-485-3p
;
hsa-mir-487a-3p
;
hsa-mir-539-3p
Nearest miRNA
hsa-mir-10393/Upstream/1563676; hsa-mir-11181/Downstream/1569720;
Nearest TSS
ENST00000557528/Upstream/28586;
ENST00000558630/Downstream/28968;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/141787
,
chr15-CpG: 32/Downstream/492484
Upstream sequence
AATGGCTAACTAAACTGTTTTCCTGCATTTCTAATACATCAATCTGTTATTTGTTTCTAGCCTGCTTTTATTGTTTCATTTTATCTGCTATTTGCACTCA
Downstream sequence
GACTTGACTTGCAGACAACCATGGGCAGCACAGTTGGGTATAAAAGAGAGTTATTTAATGGTGTTATTTAAGGTGTGCACCTTAGCCATGCAGTTTACAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HTLV-1 carrier#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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