Basic Information
VIS ID
TVIS44027213
Fusion event
HTLV-1-RORA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
End
61027137/60734938 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-106b-5p ; hsa-mir-92a-3p ; hsa-mir-33b-5p ; hsa-mir-129-5p ; hsa-mir-32-3p ; hsa-mir-1179 ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-let-7f-2-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-mir-98-3p ; hsa-mir-3611 ; hsa-mir-5580-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-670-3p ; hsa-mir-4698 ; hsa-mir-548aw ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-3662 ; hsa-mir-942-5p ; hsa-mir-506-5p ; hsa-mir-137 ; hsa-mir-218-5p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-4668-5p ; hsa-mir-3613-5p ; hsa-mir-4786-3p ; hsa-mir-4635 ; hsa-mir-4781-3p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-7109-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-758-3p ; hsa-mir-1290 ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-3171 ; hsa-mir-873-5p ; hsa-mir-1246 ; hsa-mir-8076 ; hsa-mir-144-3p ; hsa-mir-101-3p ; hsa-mir-4536-5p ; hsa-mir-3924 ; hsa-mir-1277-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-621 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-3646 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-18a-5p ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-2054 ; hsa-mir-7848-3p ; hsa-mir-4641 ; hsa-mir-656-3p ; hsa-mir-504-5p ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-155-5p ; hsa-mir-4775 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-483-3p ; hsa-mir-4725-5p ; hsa-mir-4750-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-377-3p ; hsa-mir-449c-3p ; hsa-mir-6740-3p ; hsa-mir-8086 ; hsa-mir-6870-3p ; hsa-mir-622 ; hsa-mir-154-3p ; hsa-mir-4643 ; hsa-mir-466 ; hsa-mir-4789-3p ; hsa-mir-485-3p ; hsa-mir-487a-3p ; hsa-mir-539-3p
Nearest miRNA
hsa-mir-10393/Upstream/1563676; hsa-mir-11181/Downstream/1569720;
Upstream sequence
AATGGCTAACTAAACTGTTTTCCTGCATTTCTAATACATCAATCTGTTATTTGTTTCTAGCCTGCTTTTATTGTTTCATTTTATCTGCTATTTGCACTCA
Downstream sequence
GACTTGACTTGCAGACAACCATGGGCAGCACAGTTGGGTATAAAAGAGAGTTATTTAATGGTGTTATTTAAGGTGTGCACCTTAGCCATGCAGTTTACAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate